June 24-25 | Boston

i2b2: Digital Twin and the Future of AI in Medicine

 Meeting slides are posted and recordings to be posted soon!

June 24 Morning Session

Welcome – Symposium overview: Diane Keogh

Remarks and Keynote Introduction: HMS, Dean for Research Initiatives and Global Programs, David Golan, MD, PhD

Keynote: MassCPR, Massachusetts Commissioner of Public Health, Robbie Goldstein, MD, PhD.

Panel Discussion – Better together: the promise and challenges of linking hospital and public health data.

  • Moderator – Nadine Fornelos Martins, PhD, Executive Director of Research Initiatives for MassCPR, Harvard Medical School
  • Shoba Nair, PhD, Director of Epidemiology, Boston Public Health Commission
  • Kris Cyr, Data Strategy Director, Massachusetts Department of Public Health
  • Jonathan Li, MD, Associate Professor of Medicine, Brigham and Women’s Hospital
  • Bill Adams, MD, Professor of Pediatrics, Boston University Chobanian & Avedisian School of Medicine
  • Griffin Weber, MD, PhD, Associate Professor of Medicine, Beth Israel Deaconess Medical Center

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Fireside Chat – Generative AI in medicine, from general capability to optimal personalization: Isaac Kohane MD, PhD and Chris White, PhD

Large Language Model expert panel

  • Moderator – Isaac Kohane, MD. PhD.
  • Adam Rodman, MD, BIDMC – Medical Performance 
  • Marinka Zitnick, PhD, DBMI – Data 
  • Arjun (Raj) Manrai, PhD, DBMI – Images 
  • Shawn Murphy, MD, PhD, MGB – Chart Review

Sponsors

Snowflake

Persistent Systems

June 24 Afternoon Session

Intro to the afternoon session: Linking it all together Griffin Weber, MD, PhD

Next Generation ENACT Network Shyam Visweswaran, MD, PhD and Jeff Klann, PhD.

AI/MI – Digital Twin Journey Shawn Murphy, MD, PhD and Griffin Weber, MD, PhD.

Computational Phenotype Pipeline for i2b2. Griffin Weber, MD, PhD

  Slides

See what’s new in i2b2: Overview of the new release Jeff Klann, PhD.

Scalable Deployment of i2b2 for Supporting Self-Service Query Capabilities Across Multi-Institutional Clinical Research Network, Abu Mosa, PhD.

Closing remarks: Diane Keogh

June 25 Morning Session

Working Groups

UI Working Group Update – Griffin Weber, MD, PhD.

New i2b2 Demo – Anupama Maram

Ontology Working Group Update – Michele Morris

Ontology Working Group – Incremental Data Refresh –  Michael Lin

Computed Phenotypes and use of Loyalty Cohorts

Computed Phenotypes – Griffin Weber, MD, PhD.

Loyalty Cohorts – Jeff Klann, PhD.

The German National Emergency Department Registry: The Long way to Smart Data for a learning health system. Jonas Bienzeisler M.Sc. and Raphael W. Majeed

June 25 Afternoon Session

ML API for i2b2 – Kavishwar Wagholikar, PhD

Chart review using LLM –  Nich Wattanasin

Precision is the Future of Phenotyping with AI – Hossein Estiri, PhD

Generative AI for Precision Medicine – Santosh Dixit, PhD, Persistent Systems

Future of i2b2: Towards Useful GenAI

Large Language Models: The Future of the i2b2 Query Tool – Shawn Murphy, MD, PhD

Demonstration of the orchestration layer of i2b2 workflow modeling – Shawn Murphy, MD, PhD

Demonstration of the working building blocks of an automated query system – Mike Mendis and Nicholai Mitchko

Computable Phenotype Feature Selection with LLMs –  Victor Castro

Why foundation models fail to consistently map relevant features – Chris Connor

Discussion on future focus areas for LLMs in i2b2 – Qi Li, MD