Informatics for Integrating Biology & the Bedside, or i2b2 is an NIH-funded enterprise clinical research platform, which contains a database model, application layer, and core APIs.

The i2b2 Software

tranSMART is a suite of data exploration, visualization, and ETL tools, which were developed by pharma for translational research studies.

The tranSMART Software


COVID-19 Virtual Datathon-2020

The i2b2 tranSMART Foundation in partnership with Axiomedix and the Open Source Pharma Foundation (OSPF) are holding a Covid-19 Virtual Datathon-2020 on November 18-20, 2020.

The i2b2 tranSMART Foundation, with support from a grant from Dell Technologies, is creating a public instance of the latest version (v19.1) of the Foundation’s tranSMART software.  Hosted on AWS, tranSMART will be accessible freely with a link to an open-data collection of virus datasets, curated from GEO and other sources.  In addition, all of the additional almost 400 open tranSMART datasets may be loaded.

Data in the tranSMART Open Data Library, including data on a number of diseases areas including covid-19, may be loaded into the public tranSMART or downloaded to be used in another public or private version of tranSMART.

Visit the Virtual Datathon-2020 Webpages

COVID-19 4CE Consortium

Dr. Zak Kohane and several members of our Board of Directors have launched an urgent initiative with organizations around the world to rapidly collect aggregate data on hospitalized patients that are COVID-19 positive. The goal of this effort is to quickly collect data and publish the results.
Consortium for Clinical Characterization of Covid19 by EHR (4CE)

In this time of great need, the i2b2 tranSMART Foundation and the i2b2 community are working to combine national and international data for analyses of the COVID-19 affliction on our patients.

The 4CE Consortium is a globally distributed collaboration across health centers. In this first phase we are reaching out to other collaborators to join our 96 hospital collaboration who also have EHR data to share to augment the breadth and depth of the analyses we jointly work on.

Connect to 4CE

FALL 2020 European Virtual Symposium

Our FALL 2020 European Virtual Symposium was held on November 9, 2020.

The slide decks and recordings are available from the link below.

See the slide decks and recordings

Harvard Symposium Virtual Conference

The on-site Harvard Symposium was presented on June 11-12, 2020 as a Virtual Conference. The focus was on the COVID-19 virus. We had a great conference. If you missed it or are interested in reviewing the slide decks and recordings, visit the Symposium web pages. They are partially loaded and more coming …

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Virtual Poster Session
2020 Event Sponsors


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Diane Keogh
Executive Director

From The Executive Director’s Desk

COVID-19 Action!

In this time of great need, the i2b2 community is working to combine national and international analyses of the COVID-19 affliction on our patients.

There are two major initiatives that the Foundation is participating in at this time.

Grant to the Foundation from Dell Technologies

First, we are delighted to announce that Dell Technologies has given the Foundation a significant grant to expedite three projects that are focused on COVID-19 research working towards better understanding diagnosis, treatment and prevention of the disease. The three projects will be described in detail in upcoming Community Meetings. They are:

  • Public tranSMART v19 platform running on AWS with datasets that become publicly available. This project is in collaboration with Axiomedix.
  • With the explosion of articles and research labs studying the corona virus (over 6,000 articles from 25,000 authors), a special version of Profiles is being developed by Griffin Weber and will be available publicly.
  • i2b2 and tranSMART are being synchronized to the same data model so that direct data sharing will be possible between the Foundation platforms. We will have a few use cases and sample deployments available in the coming months.

4CE Consortium

Second, I want to tell you about the 4CE Consortium that was launched by Dr. Zak Kohane and several members of our Board of Directors. This urgent initiative with organizations around the world allowed labs with i2b2 to rapidly collect aggregate data on hospitalized patients that are COVID-19 positive. Their first publication is available as a preprint (click here) and will be published soon.

i2b2 ACT COVID ontology that has been developed

An initial ACT COVID ontology has been developed by the ACT Harmonization Committee. Note: Implementing this ontology is not necessary for this initial submission, but it might be helpful for you to look at the codes it uses as you try to identify your population of COVID-19 positive patients. click here for ACT COVID ontology

More information will be published here on our website as it becomes available. Be sure to join our Community Meetings and please attend the 2020 Harvard Virtual Symposium which will include focused sessions on these and other COVID-19 related projects.


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i2b2 tranSMART Foundation launches Covid

The future of i2b2 is more truth from data, better user experiences, and more community engagement. #i2b2tsEurope2020

Peter Rice and Rudy Potenzone talk about what's next for the i2b2tranSMART Foundation. Join a working group, we want to hear from you.

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