June 24-25 | Boston

i2b2: Digital Twin and the Future of AI in Medicine

 Meeting slides are posted and recordings to be posted soon!

June 24 Morning Session

Welcome – Symposium overview: Diane Keogh

Remarks and Keynote Introduction: HMS, Dean for Research Initiatives and Global Programs, David Golan, MD, PhD

Keynote: MassCPR, Massachusetts Commissioner of Public Health, Robbie Goldstein, MD, PhD.

Panel Discussion – Better together: the promise and challenges of linking hospital and public health data.

  • Moderator – Nadine Fornelos Martins, PhD, Executive Director of Research Initiatives for MassCPR, Harvard Medical School
  • Shoba Nair, PhD, Director of Epidemiology, Boston Public Health Commission
  • Kris Cyr, Data Strategy Director, Massachusetts Department of Public Health
  • Jonathan Li, MD, Associate Professor of Medicine, Brigham and Women’s Hospital
  • Bill Adams, MD, Professor of Pediatrics, Boston University Chobanian & Avedisian School of Medicine
  • Griffin Weber, MD, PhD, Associate Professor of Medicine, Beth Israel Deaconess Medical Center

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Fireside Chat – Generative AI in medicine, from general capability to optimal personalization: Isaac Kohane MD, PhD and Chris White, PhD

Large Language Model expert panel

  • Moderator – Isaac Kohane, MD. PhD.
  • Adam Rodman, MD, BIDMC – Medical Performance 
  • Marinka Zitnick, PhD, DBMI – Data 
  • Arjun (Raj) Manrai, PhD, DBMI – Images 
  • Shawn Murphy, MD, PhD, MGB – Chart Review

Sponsors

Snowflake

Persistent Systems

June 24 Afternoon Session

Intro to the afternoon session: Linking it all together Griffin Weber, MD, PhD

Next Generation ENACT Network.

ENACT: Evolve to Next-Gen ACT- Shyam Visweswaran, MD, PhD.

ENACT Data Quality Explorer Demo

Data Quality – Jeff Klann, PhD.

AI/MI – Digital Twin Journey Shawn Murphy, MD, PhD and Griffin Weber, MD, PhD.

Computational Phenotype Pipeline for i2b2. Griffin Weber, MD, PhD

  Slides

Development of Digital Twin for i2b2. Shawn Murphy, MD, PhD.

  Slides

See what’s new in i2b2: Overview of the new release Jeff Klann, PhD.

Scalable Deployment of i2b2 for Supporting Self-Service Query Capabilities Across Multi-Institutional Clinical Research Network, Abu Mosa, PhD.

June 25 Morning Session

Working Groups

UI Working Group Update – Griffin Weber, MD, PhD.

New i2b2 Demo – Anupama Maram

Ontology Working Group Update – Part 1 – Michele Morris

Ontology Working Group – Incremental Data Refresh –  Michael Lin and Carmen Vodislav

Ontology Working Group Update – Part 2 – Michele Morris

Computed Phenotypes and use of Loyalty Cohorts

Computed Phenotypes – Griffin Weber, MD, PhD.

Loyalty Cohorts – Jeff Klann, PhD.

The German National Emergency Department Registry: The Long way to Smart Data for a learning health system. Jonas Bienzeisler M.Sc. and Raphael W. Majeed

June 25 Afternoon Session

ML API for i2b2 – Kavishwar Wagholikar, PhD

Chart review using LLM –  Nich Wattanasin

Precision is the Future of Phenotyping with AI – Hossein Estiri, PhD

Generative AI for Precision Medicine – Santosh Dixit, PhD, Persistent Systems

Future of i2b2: Towards Useful GenAI

Large Language Models: The Future of the i2b2 Query Tool – Shawn Murphy, MD, PhD

Demonstration of the orchestration layer of i2b2 workflow modeling – Shawn Murphy, MD, PhD

Demonstration of the working building blocks of an automated query system – Mike Mendis and Nicholai Mitchko

Refinement of AI ontology navigation and ways to evaluate it – Victor Castro 

Why foundation models fail to consistently map relevant features – Chris Connor

Discussion on future focus areas for LLMs in i2b2 – Qi Li, MD