AI-powered public health intelligence, built on i2b2

2026 Symposium

June 9 – 10 | Boston

AI-powered public heath intelligence, built on i2b2

Save the date, more details coming soon!

Join us in Boston on June 9–10 for the 2026 i2b2 Foundation Symposium, where experts in informatics, epidemiology, AI, and public health will showcase how i2b2 is powering realtime disease surveillance and nextgeneration population health intelligence. The program highlights AIenabled computed phenotypes, federated queries across large populations, and new temporal and spatial visualizations that turn EHR and public health data—including wastewater signals—into rapid, actionable insights.
Day 2 offers deepdive use cases and handson sessions for the upcoming 1.8.3 release, with both a technical track and a clinical researcher track. See the latest capabilities in action and learn directly from the teams advancing the platform.
i2b2 release 1.8.2 is now available!

This major open-source update is packed with critical upgrades, performance enhancements, and  powerful new features to support clinical and translational research worldwide.

What you you can expect:

  • Secure Software Framework updates
  • Faster Patient Counting Scripts
  • ACT Ontology v4.2 Integration
  • New Data Export Workflow
  • Enhanced Performance
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What’s New

i2b2 1.8.2 release
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Community Meetings

Next  Meeting – March 17, 2026
12:00 – 1:00 PM EST
Past meeting slides & recordings
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i2b2 User Tutorials

Video tutorials and i2b2 Quick Guides

Available here!

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Need i2b2 support

See our list of Contractors

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i2b2 Software

Documentation
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try the demo

SHRINE Software

Documentation
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tranSMART Software

Documentation
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i2b2 tranSMART Chairman of the Board

Congratulations to Zak on the recent publication of The AI REVOLUTION in MEDICINE: GPT-4 AND BEYOND and added title of Editor-In-Chief of a new journal from the New England Journal of Medicine entitled NEJM AI

Image of the book cover for The AI Revolution in Medicine: GPT-4 and Beyond

Isaac Kohane, MD Ph D

Chair of the Department of Biomedical Informatics, Harvard Medical School

Marion V. Nelson Professor of Biomedical Informatics, Harvard Medical School

Associate Professor of Medicine, Brigham and Women’s Hospital

More Information <

Impact Genome Insight (Jan 2026)

The I2B2 Foundation supports healthcare systems in incorporating their Computational Phenotype Pipeline into their work to support research. To date, six hospitals have adopted the system, which enables them to access an open-source database and advanced analytics that were not previously available. The use of this system will increase efficiency in medical research, which will be the focus of additional evaluation in the future.

Click the Impact Verified logo to see our Verified Impact Report.

With generous support from

Genome Impact 2026 Certification Seal

History

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Working Groups

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Board of Directors

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Open Source Licensing

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Sponsors

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Community

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Diane Keogh
Executive Director
Diane.Keogh@i2b2transmart.org

From The Executive Director’s Desk

Welcome to an Exciting 2025!

This year promises to be a transformative one as we continue our mission of advancing translational research through cutting-edge technology, global collaborations, and community-driven initiatives.

Strategic Updates from Our Board of Directors

Our Board of Directors remains a cornerstone of our success, guiding us with expertise from academic medical centers and industry leaders across the U.S. and Europe. Their strategic vision drives innovation and strengthens our foundation’s global impact.

Meet our Board members Click HERE

Revolutionizing Healthcare with Dell Technologies

We are thrilled to extend our collaboration with Dell Technologies, which supports the groundbreaking Personalized Digital Medical Twin initiative.

Key Highlights:

  • Explainable AI Integration: Harnessing transparent AI for more accurate patient representations, paving the way for precise cohort identification in clinical trials.
  • Computed Phenotypes in Action: i2b2 v1.8.1 introduces algorithms that deliver deeper insights into patient conditions and empower clinical decision-making.

Save the Date: 2025 i2b2 tranSMART Symposium, June 9-10, 2025 | Boston, MA

Join thought leaders and innovators in translational research for two days of inspiration, learning, and collaboration.

Agenda Highlights:

  • Keynote Speaker: Dr. Zak Kohane on “Human Values Project: The AI We Want for the Research We Need”.
  • Spotlight on Innovations: Explore computed phenotypes and the transformative Digital Twin initiative.
  • Real-World Use Cases: Learn how i2b2 tools are reshaping clinical research.
  • Working Groups & Roadmaps: Discover community efforts and future directions in research informatics.

Mark your calendar and join us for this can’t-miss event!

Introducing i2b2 v1.8.1: Innovation at Your Fingertips

We’re proud to announce the release of i2b2 v1.8.1, a leap forward in usability and functionality.

Top Features:

  • Modern Interface: A sleek, intuitive design for an effortless user experience.
  • OMOP Compatibility: Seamless integration for OHDSI community users.
  • Loyalty Cohorts: Enhanced cohort development and management tools.
  • Data Quality Insights: Tools to ensure the reliability of your data.
  • Bulk Exporter: Simplified data export for analysis and reporting.

Coming Soon: Stay tuned for v1.8.2 and its exciting new features!

Expanding Horizons with the EnACT Network

The rollout of i2b2 v1.8.1 across the EnACT network marks a significant milestone, extending the reach of computational phenotypes and advancing translational research nationwide.

We Want to Hear from You!

Your input drives our success. Share your thoughts, join our initiatives, or simply reach out.
Contact us: Click HERE

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